We compare the difference between Sentinel vs Interceptor. Both products are made made Novartis Animal Health and have very similar looking packets. But the main difference between Sentinel and Interceptor, is that Sentinel treats for fleas long-term and controls flea allergy dermatitis. Sentinel will not kill adult fleas, but it will control flea infestations. Interceptor does not treat for fleas of any sort.
What Interceptor and Sentinel have in common is they are both a monthly chewable tablet. They prevent heartworm infection in dogs. They control adult roundworm, immature roundworm, adult whipworm, adult hookworm and adult tapeworm in dogs. Sentinel Spectrum contains lufenuron to treat for fleas and milbemycin oxime & praziquantel to treat for worms. Interceptor Spectrum uses milbemycin oxime & praziquantel to treat for worms. You should have your dog tested for heartworm disease before using either of these products.
Interceptor Spectrum and Sentinel Spectrum are both color coded the same to match the weight ranges and dosage amounts. The sizes, color and ingredients are as follows:
Product |
Weight Range |
Color Pack |
Lufenuron |
Melbemycin oxime |
Praziquantel |
| Interceptor |
up to 9lbs (up to 4kgs) |
Orange |
None |
2.3 mg |
22.8 mg |
| Sentinel |
up to 9lbs (up to 4kgs) |
Orange |
46 mg |
2.3 mg |
22.8 mg |
| Interceptor |
9-23lbs (4-11kgs) |
Green |
None |
5.75 mg |
57 mg |
| Sentinel |
9-23lbs (4-11kgs) |
Green |
115 mg |
5.75 mg |
57 mg |
| Interceptor |
24-48lbs (11-22kgs) |
Yellow |
None |
11.5 mg |
114 mg |
| Sentinel |
24-48lbs (11-22kgs) |
Yellow |
230 mg |
11.5 mg |
114 mg |
| Interceptor |
49-99lbs (22-45kgs) |
White/Blue |
None |
23 mg |
228 mg |
| Sentinel |
49-99lbs (22-45kgs) |
White/Blue |
460 mg |
23 mg |
228 mg |
Sentinel Spectrum and Interceptor Spectrum both come in the form of chewable tablets that should be given with a full meal of food. Interceptor can be given to puppies from 2 weeks of age and Sentinel can be given to puppies from 6 weeks of age. You can buy Sentinel & Interceptor in a single dose which will treat 1 dog for 1 month, 3 pack which will treat 1 dog for 3 months, 6 pack which will treat 1 dog for 6 months and 12 pack which will treat 1 dog for 12 months.
Compare Sentinel vs Interceptor below in this detailed chart with what each product does and doesn't do:
Component |
Sentinel Spectrum for Dogs |
Interceptor Spectrum for Dogs |
| Adult Fleas |
No |
No |
| Flea Eggs |
No |
No |
| Adult Larvae |
Yes |
No |
| Flea Allergy Dermatitis |
Yes |
No |
| Ticks |
No |
No |
| Heartworm |
Yes |
Yes |
| Roundworm |
Yes |
Yes |
| Hookworm |
Yes |
Yes |
| Whipworm |
Yes |
Yes |
| Tapeworm |
Yes |
Yes |
| Sarcoptic Mange |
No |
No |
| Earmites |
No |
No |
| Lice |
No |
No |
| Insects |
No |
No |
| Price Monthly From |
$17.95 |
$8.95 |
Overall in this product comparison Sentinel will treat for fleas, heartworm and intestinal worms and Interceptor will treat for just heartworm and intestinal worms. Interceptor is obviously much cheaper as it does not contain the flea component that Sentinel does. Each of these products work well for treating worms in dogs and are easy to dose your dog with. To learn more about Sentinel Spectrum see
Sentinel for dogs frequently asked questions and to learn more about Interceptor spectrum see
Interceptor for dogs frequently asked questions.